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Reactome

About this network

This is a network of protein–protein interactions in the species Homo sapiens, i.e., in Humans. The data is curated by the Reactome project, an open online database of biological pathways.

Network info

CodeRC
Category Metabolic
Date of origin2014
Data source http://www.reactome.org/pages/download-data/
Vertex type Protein
Edge type Interaction
FormatUndirected: Edges are undirected Undirected
Edge weightsUnweighted: Simple edges Unweighted
Metadata Loops:  An edge may connect a node with itself Loop
Size6,327 vertices (proteins)
Volume147,547 edges (interactions)
Average degree46.640 edges / vertex
Fill0.0073705 edges / vertex2
Maximum degree855 edges
Size of LCC5,973 vertices
Wedge count20,746,788
Claw count1,500,721,941
Triangle count4,187,734
Square count521,539,475
4-tour count4,255,595,272
Power law exponent (estimated) with dmin1.7410 (dmin = 17)
Gini coefficient65.7%
Relative edge distribution entropy91.2%
Assortativity0.24487
Clustering coefficient60.6%
Diameter24 edges
90-percentile effective diameter5.39 edges
Mean shortest path length4.14 edges
Spectral norm208.17
Algebraic connectivity0.013403
Degree distribution of the Reactome network
Degree distribution
Degree distribution of the Reactome network
Degree distribution
Degree distribution of the Reactome network
Degree distribution
Clustering coefficient distribution of the Reactome network
Clustering coefficient distribution
Distance distribution of the Reactome network
Distance distribution
Distance distribution on a logistic scale of the Reactome network
Distance distribution on a logistic scale
Top-k eigenvalues of A of the Reactome network
Top-k eigenvalues of A
Top-k eigenvalues of N of the Reactome network
Top-k eigenvalues of N
Top-k eigenvalues of L of the Reactome network
Top-k eigenvalues of L
Spectral distribution of the eigenvalues of A of the Reactome network
Spectral distribution of the eigenvalues of A
Spectral distribution of the eigenvalues of N of the Reactome network
Spectral distribution of the eigenvalues of N
Spectral distribution of the eigenvalues of L of the Reactome network
Spectral distribution of the eigenvalues of L
Cumulative spectral distribution of A of the Reactome network
Cumulative spectral distribution of A
Cumulative spectral distribution of N of the Reactome network
Cumulative spectral distribution of N
Cumulative spectral distribution of L of the Reactome network
Cumulative spectral distribution of L

Downloads

TSV file:downloadreactome.tar.bz2 (373.09 KiB)

References

[1] Reactome network dataset -- KONECT, October 2016. [ http ]
[2] G. Joshi-Tope, Marc Gillespie, Imre Vastrik, Peter D'Eustachio, Esther Schmidt, Bernard de Bono, Bijay Jassal, GR Gopinath, GR Wu, Lisa Matthews, et al. Reactome: A knowledgebase of biological pathways. Nucleic Acids Research, 33(suppl 1):D428--D432, 2005.

BibTeX